Prevalence of HIV as a percentage of population aged 15-49 years fell 0.543% to 18.3% in South Africa in 2021, according to World Bank / WHO.
Historically, prevalence of HIV as a percentage of population aged 15-49 years in South Africa reached an all time high of 18.6% in 2018 and an all time low of 0.800% in 1990. When compared to South Africa's main peers, prevalence of HIV as a percentage of population aged 15-49 years in Botswana amounted to 18.6%, 20.9% in Lesotho, 11.8% in Namibia and 27.9% in Swaziland in 2021.
South Africa has been ranked 4th within the group of 136 countries we follow in terms of prevalence of HIV as a percentage of population aged 15-49 years.
| Prevalence of HIV, Total (As % of Population Aged 15-49) | Unit | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 |
| Angola | % | 1.90% | 1.80% | 1.80% | 1.70% | 1.70% | ||||||||||||||||
| Botswana | % | 21.7% | 21.3% | 20.9% | 20.4% | 19.8% | ||||||||||||||||
| Lesotho | % | 24.6% | 24.2% | 23.6% | 23.0% | 22.3% | ||||||||||||||||
| Mozambique | % | 12.0% | 12.0% | 11.9% | 11.8% | 11.7% | ... | |||||||||||||||
| Namibia | % | 13.1% | 12.9% | 12.8% | 12.6% | 12.4% | ||||||||||||||||
| South Africa | % | 18.2% | 18.4% | 18.5% | 18.6% | 18.6% | ||||||||||||||||
| Swaziland | % | 29.6% | 29.8% | 29.7% | 29.4% | 29.1% | ||||||||||||||||
| Zambia | % | 12.6% | 12.4% | 12.2% | 12.0% | 11.6% | ||||||||||||||||
| Zimbabwe | % | 14.2% | 13.8% | 13.4% | 13.0% | 12.5% |
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